Global Entry Program: it is necessary to have frequent trips to be granted Global Entry, generally, it requires completing minimum requirements as mentioned above.
Sentri Program: Sentri has an automated system that identifies transit vehicles and allows you to drive the Mariano border in Tijuana without announcing your personal or customs documents to obtain Global Entry within the United States.
Global Entry vs Sentri are different options depending on whether the visitor is a frequent traveler or not, Global Entry is for the visitor who needs to process many international documents when crossing the border and registration is presented as an option. Sentri, on the other hand, has the advantages of saving time and adequate effort only if the passengers are frequent, with maximum global internalization permissiveness without announcing their personal or customs documents when driving the Mariano border, in Tijuana.